Dan Caten is one of two brothers who created DSquared², a fashion label. In 1991, Dean and Dan Caten moved to Milan, Italy to pursue their dreams of fashion and creating their own company. In 1995, they debuted their very first men's collection, and in 2003, the very first women's collection debuted as well.

Since then, DSquared²'s fashion lines have been worn by celebrities such as Justin Timberlake, Lenny Kravitz, and Madonna. In 2002, the brothers designed over 150 pieces for Madonna's Drowned World Tour and "Don't Tell Me" music video.